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1. Lab 8 Digestion

2. Lab 8: Digestion • Histology • Parotid gland, esophagus, stomach, duodenum, jejunum, ileum, colon, liver, pancreas • Alimentary canal histological layers • Models of the digestive system • PhysioEx: Chemical and Physical Processes of Digestion • Learn to understand and interpret data tables + simulated test tube results for salivary amylase • Learn about the major digestive enzymes and their substrates • Examine the effect of heating, cooling, and pH on enzyme activity • Use indicators of enzyme activity (IKI, Benedict’s, etc.)

3. General Structure • Digestive organs divided into 2 main groups • GI (alimentary) tract • Accessory structures • cheeks, teeth, tongue, salivary glands • liver, gallbladder, pancreas

4. General Organization of GI Tract

5. Histology of the GI Tract #55: salivary glands #56: esophagus #57: stomach #58: small intestine – duodenum #59: small intestine - jejunum #60: small intestine – ileum #54: liver #39: pancreas #61: large intestine

6. Salivary Glands MA = mucous acinus; SA = serous acinus; ducts lined by simple cuboidal epithelium

7. Parotid Salivary Gland

8. Submandibular and Sublingual Salivary Glands

9. Esophagus

10. Esophagus

11. Esophagus – 4 tissue layers

12. Esophagus

13. Esophagus

14. Transition Zone Simple columnar Stratified squamous

15. Stomach

16. The interior wall of the stomach consists of a series of folds, called rugae.

17. Rugae in Cross Section

18. Rugae

19. Detail of Rugae

20. Fundus:gastric glands

21. Gastric Glands

22. G Cells produce Gastrin

23. Duodenum

24. Duodenum

25. Villi (multicellular)

26. Duodenum

27. Villi and Intestinal Crypts

28. Duodenum

29. Jejunum

30. Jejunum

32. Ileum with MALT = Mucosal Associated Lymphatic Tissue

33. Ileum

34. Ileum with Peyer’s Patches = aggregated lymphatic nodules

35. Ileum

36. Ileum and Plicae Circularies Lacteal

37. Ileum Diffuse Lymphatic Tissue Lymphatic Nodule with Germinal Center

38. Liver in cross section

40. Liver Lobules

41. Liver Parenchyma

42. Hepatocytes

43. Liver Lobule

44. Hepatic Triad

45. Stellate Reticuloendothelial Cell monocyte-derived fixed macrophages (aka Kupffer cells)

46. Pancreas

47. Pancreas Exocrine: acinar cells Endocrine: islet cells

49. Pancreas Acinar Cells

50. Large Intestine(Colon)

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